If you are currently being treated with any of the following medications, you should not use uva ursi without first talking to your healthcare provider.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Corticosteroids
Based upon animal studies conducted in Japan, uva ursi may increase the anti-inflammatory effects of corticosteroid medications (such as prednisolone and dexamethasone) and nonsteroidal anti-inflammatory drugs (NSAIDs; commonly used for pain and inflammation, including ibuprofen and indomethacin). Additional studies are needed to confirm whether uva ursi could increase the effects of these medications in people.